UVI 3003

CAS No. 847239-17-2

UVI 3003( —— )

Catalog No. M24839 CAS No. 847239-17-2

UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 40 In Stock
5MG 61 In Stock
10MG 110 In Stock
25MG 230 In Stock
50MG 385 In Stock
100MG 575 In Stock
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Biological Information

  • Product Name
    UVI 3003
  • Note
    Research use only, not for human use.
  • Brief Description
    UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
  • Description
    UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy|RXRα
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    847239-17-2
  • Formula Weight
    436.58
  • Molecular Formula
    C28H36O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (229.05 mM; Need ultrasonic)
  • SMILES
    CCCCCOC1=C(C2=CC(/C=C/C(O)=O)=CC=C2O)C=C3C(C(C)(CCC3(C)C)C)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhu J, et al. The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis. Toxicol Appl Pharmacol. 2017 Jan 1;314:91-97.
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