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UVI 3003
CAS No. 847239-17-2
UVI 3003 ( —— )
Catalog No. M24839 CAS No. 847239-17-2
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 230 | In Stock |
|
| 50MG | 385 | In Stock |
|
| 100MG | 575 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUVI 3003
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NoteResearch use only, not for human use.
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Brief DescriptionUVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
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DescriptionUVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorAutophagy;RXRα
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Research Area——
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Indication——
Chemical Information
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CAS Number847239-17-2
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Formula Weight436.6
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Molecular FormulaC28H36O4
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (229.05 mM; Need ultrasonic)
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SMILESCCCCCOC1=C(C2=CC(/C=C/C(O)=O)=CC=C2O)C=C3C(C(C)(CCC3(C)C)C)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhu J, et al. The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis. Toxicol Appl Pharmacol. 2017 Jan 1;314:91-97.
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UVI 3003
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
